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Antigenic Specificity | Bak |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Bak protein. In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.Takuma Uo, J. Biol. Chem., Mar 2005; 280: 9065 - 9073.Pierre-Fran ois Cartron, Mol. Cell. Biol., Jul 2003; 23: 4701 - 4712.Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.Neil A. Jones, Mol. Pharmacol., May 1998; 53: 819. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human Bak. |
Other Names | [Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like 7 protein; BAK1; BAK] |
Gene, Accession # | [Bak], Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
Catalog # | MBS9409316 |
Price | $200, $255 |
Order / More Info | Bak Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |