Dystrophin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDystrophin
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as alpha-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (my
ImmunogenImmunogen: E Coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin. Ig Type: Rabbit IgG
Other Names[Dystrophin; Apo dystrophin; BMD; CMD3B; DMD; DMD_HUMAN; Duchenne muscular dystrophy protein; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; Dystrophin; Muscular dystrophy Duchenne and Becker types; dystrophin], [DMD; DMD; BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272]
Gene, Accession #Gene ID: 1756, NCBI: NP_000100.2, UniProt: P11532
Catalog #MBS177765
Price$315
Order / More InfoDystrophin Antibody from MYBIOSOURCE INC.
Product Specific References1. Tennyson CN, Klamut HJ, Worton RG (1995). The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced. Nature Genetics 9 (2): 184-90. 2. Garcia-Pelagio KP, Bloch RJ, Ortega A, Gonzalez-Serratos H (2011). Biomechanics of the sarcolemma and costameres in single skeletal muscle fibers from normal and dystrophin- null mice. J Muscle Res Cell Motil 31 (5-6): 323-336. 3. Strachan T and Read AP, 1999. Human molecular genetics, BIOS Scientific, New York, USA
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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