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Antigenic Specificity | Dystrophin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as alpha-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (my |
Immunogen | Immunogen: E Coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin. Ig Type: Rabbit IgG |
Other Names | [Dystrophin; Apo dystrophin; BMD; CMD3B; DMD; DMD_HUMAN; Duchenne muscular dystrophy protein; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; Dystrophin; Muscular dystrophy Duchenne and Becker types; dystrophin], [DMD; DMD; BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272] |
Gene, Accession # | Gene ID: 1756, NCBI: NP_000100.2, UniProt: P11532 |
Catalog # | MBS177765 |
Price | $315 |
Order / More Info | Dystrophin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Tennyson CN, Klamut HJ, Worton RG (1995). The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced. Nature Genetics 9 (2): 184-90. 2. Garcia-Pelagio KP, Bloch RJ, Ortega A, Gonzalez-Serratos H (2011). Biomechanics of the sarcolemma and costameres in single skeletal muscle fibers from normal and dystrophin- null mice. J Muscle Res Cell Motil 31 (5-6): 323-336. 3. Strachan T and Read AP, 1999. Human molecular genetics, BIOS Scientific, New York, USA |