Rab5A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRab5A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: Rab5A antibody detects endogenous levels of total Rab5A. Description: Required for the fusion of plasma membranes and early endosomes.Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978
ImmunogenImmunogen: A synthesized peptide derived from human Rab5A Subcellular Location: Cell Membrane. Early Endosome Membrane. Melanosome. Enriched in stage I melanosomes. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Bovine (92%), Horse (100%), Sheep (92%), Rabbit (92%), Dog (100%), Chicken (83%)
Other Names[RAB 5; RAB 5A; RAB5A; RAB5A member RAS oncogene family; RAB5A_HUMAN; RAS associated protein RAB5A; Ras related protein Rab 5A; Ras-related protein Rab-5A]
Gene, Accession #[Rab5A], Gene ID: 5868, NCBI: NP_001278977.1, UniProt: P20339
Catalog #MBS9601277
Price$240, $280
Order / More InfoRab5A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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