Edit |   |
Antigenic Specificity | Rab5A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rab5A antibody detects endogenous levels of total Rab5A. Description: Required for the fusion of plasma membranes and early endosomes.Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978 |
Immunogen | Immunogen: A synthesized peptide derived from human Rab5A Subcellular Location: Cell Membrane. Early Endosome Membrane. Melanosome. Enriched in stage I melanosomes. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Bovine (92%), Horse (100%), Sheep (92%), Rabbit (92%), Dog (100%), Chicken (83%) |
Other Names | [RAB 5; RAB 5A; RAB5A; RAB5A member RAS oncogene family; RAB5A_HUMAN; RAS associated protein RAB5A; Ras related protein Rab 5A; Ras-related protein Rab-5A] |
Gene, Accession # | [Rab5A], Gene ID: 5868, NCBI: NP_001278977.1, UniProt: P20339 |
Catalog # | MBS9601277 |
Price | $240, $280 |
Order / More Info | Rab5A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |