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Antigenic Specificity | UBAP2L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: UBAP2L antibody is human and mouse reactive. At least four isoforms of UBAP2L are known to exist; this antibody will detect all four isoforms. This antibody is predicted to not cross-react with UBAP2. The UBA domain-containing protein ubiquitin associated protein 2-like (UBAP2L), also known as NICE4, is a ubiquitously expressed 1,087 amino acid protein. UBAP2L is preferentially expressed in hematopoietic stem cell (HSC) populations and interacts with BMI1, a well-known determinant of HSC function (1). It is essential for the activity of long-term repopulating HSCs but not the BMI1-dependent repression of the Ink4a/Arf locus (1). |
Immunogen | Immunogen: UBAP2L antibody was raised against a 19 amino acid peptide from near the amino terminus of human UBAP2L. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: HeLa Cell Lysate |
Other Names | [Ubiquitin associated protein 2-like, NICE-4], [UBAP2L; UBAP2L; NICE4; NICE-4; KIAA0144; NICE4] |
Gene, Accession # | [UBAP2L], Gene ID: 9898, NCBI: NP_055662, UniProt: Q14157 |
Catalog # | MBS154382 |
Price | $375 |
Order / More Info | UBAP2L Antibody from MYBIOSOURCE INC. |
Product Specific References | Bordeleau ME, Aucagne R, Chagraoui J, et al. UBAPL2L is a novel BMI1-iteracting protein essential for hematopoietic stem cell activity. Blood 2014; 124:2362-9. |