COL4A3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCOL4A3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.6 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total COL4A3 protein. Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase i
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human collagen, type IV, alpha 3 (Goodpasture antigen)
Other Names[CO4A3; COL4A3; Goodpasture antigen; Tumstatin]
Gene, Accession #[COL4A3], Gene ID: 1285, NCBI: NP_000082.2, UniProt: Q01955
Catalog #MBS9402704
Price$255
Order / More InfoCOL4A3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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