AKT1 (Proto-Oncogene) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AKT1 (Proto-Oncogene) |
| Clone | [AKT1/2491] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2b, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 62kDa, which is identified as AKT1The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB? or RacPK-?) and Akt 3 (also designated PKB? or thyoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylati |
| Immunogen | Immunogen: Recombinant human AKT1 protein fragment (around aa85-189). Cellular Localization: Nuclear, Cytoplasmic and Cell Surface |
| Other Names | [AKT1; Oncogene AKT1; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Proto-oncogene c-Akt; RAC Alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha], [AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha] |
| Gene, Accession # | [AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
| Catalog # | MBS439937 |
| Price | $190, $340, $340 |
| Order / More Info | AKT1 (Proto-Oncogene) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Franke, T.F., et al. 1995. The protein kinase encoded by the Akt protoonco- gene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81: 727-736. |
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MYBIOSOURCE INC.
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