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Antigenic Specificity | rat Haptoglobin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between |
Immunogen | Immunogen: Recombinant rat Haptoglobin protein |
Other Names | [Liver regeneration-related protein LRRG173; Zonulin; Hp; Ba1-647], [Hp; Hp; Ba1-647] |
Gene, Accession # | Gene ID: 24464, NCBI: NP_036714.2, UniProt: P06866 |
Catalog # | MBS1491015 |
Price | $160, $235 |
Order / More Info | rat Haptoglobin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |