CD11a (inhibitor) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD11a (inhibitor)
Clone[NKI(SPV)-L7]
Host SpeciesMouse (Balb/c)
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC), Immunoprecipitation (IP)
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DescriptionThe monoclonal antibody SPV-L7 reacts with the alpha chain of LFA-1, the CD11a/CD18 integrin heterodimer present on Human T- and B-lymphocytes, granulocytes and monocytes. Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a Human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1
ImmunogenSource Note: The antibody was obtained by immunisation of Balb/c mice with cells of the T4+T8- cytotoxic T lymphocyte clone HG-38. The antibody was selected for inhibition of T-cell mediated killing by screening of the hybridoma supernatants 10-14 days after the fusion.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS570246
Price$415
Order / More InfoCD11a (inhibitor) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKeizer G.D., J. Borst, C.G. Figdor, H. Spits, F. Miedema, C. Terhorst, J.E. de Vries. Eur. J. Immunol. 15: 1142-1147, 1985.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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