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Antigenic Specificity | DNA Polymerase beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total DNA Polymerase b protein. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.Hiroyuki Matsumoto, Plant Cell Physiol., Nov 1981; 22: 1317 - 1324.L.K. Karagyozov, Nucleic Acids Res., Jun 1978; 5: 1907 - 1917.F Costanzo, J. Virol., Mar 1977; 21: 996 - 1001.AJ Faber, Eur. J. Biochem., Nov 1981; 120: 357. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human DNA Polymerase b. |
Other Names | [DNA Polymerase b; DNA polymerase beta; EC 2.7.7.7; EC 4.2.99] |
Gene, Accession # | Gene ID: 5423, NCBI: NP_002681.1, UniProt: P06746 |
Catalog # | MBS9412863 |
Price | $200, $255 |
Order / More Info | DNA Polymerase beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |