DRAM (NT) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DRAM (NT) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been smuggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and smuggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist. |
| Immunogen | Immunogen: DRAM antibody was raised against a 16 amino acid peptide from near the amino terminus of human DRAM. Positive Control: Western Blot: K562 cell lysateImmunohistochemistry: Human liver tissue |
| Other Names | [Damage-regulated autophagy modulator], [DRAM1; DRAM1; DRAM; DRAM] |
| Gene, Accession # | [DRAM], Gene ID: 55332, NCBI: NP_060840.2, UniProt: Q8N682 |
| Catalog # | MBS840905 |
| Price | $375 |
| Order / More Info | DRAM (NT) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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