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Antigenic Specificity | Mouse EphA2 |
Clone | [8F21] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was selected for its ability to detect mouse EphA2 in western blots. In this format, this antibody does not cross-react with recombinant mouse EphA3, 4, 6, 7, 8, and EphB1, 2, 3, 4, or 6. EphA2, also known as Eck, Myk2, and Sek2, is a member of the Eph receptor family which binds members of the ephrin ligand family. There are two classes of receptors, designated A and B. Both the A and B class receptors have an extracellular region consisting of a globular domain, a cysteine-rich domain, and two fibronectin type III domains. This is followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains a juxtamembrane motif with two tyrosine residues, which are the major autophosphorylation sites, a kinas |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with recombinant mouse EphA2 extracellular domain. IgG1 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [mouse EphA2 (#8F21)], [Epha2; Epha2; Eck; Myk2; Sek2; Sek-2; AW545284; Eck; Myk2; Sek2] |
Gene, Accession # | [EphA2], Gene ID: 13836, NCBI: NP_034269.2, UniProt: Q03145 |
Catalog # | MBS690113 |
Price | $490 |
Order / More Info | Mouse EphA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |