Active Caspase-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Active Caspase-3 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, chicken |
| Isotype | IgG1 |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous Active Caspase-3 protein. CASP3 (caspase 3) encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing |
| Immunogen | Immunogen: Recombinant Protein |
| Other Names | [Mouse Active Caspase-3] |
| Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
| Catalog # | MBS9700318 |
| Price | $250, $250 |
| Order / More Info | Active Caspase-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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