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Antigenic Specificity | HMGB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HMGB1 antibody is human, mouse and rat reactive. The high-mobility group box 1 (HMGB1) protein was originally identified as a highly conserved nuclear DNA-binding protein that participates in DNA replication, repair and transcriptional regulation of gene expression (1,2). However, HMGB1 has more recently emerged as an extracellularly released mediator of inflammation and repair responses in lipopolysaccharide (LPS)-induced endotoxemia and sepsis (3). HMGB1 has also been suggested to induce secretion of pro-inflammatory cytokines and chemokines by inducing NF-kB signaling downstream of Toll-like receptor (TLR) 2 and TLR4 activation (4). |
Immunogen | Immunogen: HMGB1 antibody was raised against a 19 amino acid peptide near the center of human HMGB1. Buffer: HMGB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [HMGB1; HMG1; HMG3; SBP-1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1; high mobility group box 1], [HMGB1; HMGB1; HMG1; HMG3; SBP-1; HMG1; HMG-1] |
Gene, Accession # | [HMGB1], Gene ID: 3146, NCBI: NP_002119, UniProt: P09429 |
Catalog # | MBS153707 |
Price | $375 |
Order / More Info | HMGB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |