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Antigenic Specificity | Human Ectonucleoside triphosphate diphosphohydrolase 5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. |
Immunogen | Immunogen: Recombinant human Ectonucleoside triphosphate diphosphohydrolase 5 protein (149-428aa) |
Other Names | [NTPDase 5; CD39 antigen-like 4; ER-UDPase; Guanosine-diphosphatase ENTPD5; GDPase ENTPD5; Nucleoside diphosphatase; Uridine-diphosphatase ENTPD5; UDPase ENTPD5; ENTPD5; CD39L4; PCPH], [ENTPD5; ENTPD5; PCPH; CD39L4; NTPDase-5; CD39L4; PCPH; NTPDase 5; GDPase ENTPD5; UDPase ENTPD5] |
Gene, Accession # | [ENTPD5], Gene ID: 957, NCBI: NP_001240.1, UniProt: O75356 |
Catalog # | MBS1492677 |
Price | $120, $160 |
Order / More Info | Human Ectonucleoside triphosphate diphosphohydrolase 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |