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Antigenic Specificity | SYK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon en |
Immunogen | Immunogen: Recombinant Human Tyrosine-protein kinase SYK protein (260-361AA) |
Other Names | [Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk; SYK] |
Gene, Accession # | [SYK], Gene ID: 6850, NCBI: NP_001128524.1, UniProt: P43405 |
Catalog # | MBS7104505 |
Price | $160, $235 |
Order / More Info | SYK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |