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Antigenic Specificity | Androgen Receptor (Phospho-Tyr363) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Androgen Receptor only when phosphorylated at tyrosine 363. The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F) derived from Human Androgen Receptor. |
Other Names | [ANDR; Androgen receptor; Dihydrotestosterone receptor; NR3C4] |
Gene, Accession # | Gene ID: 367, NCBI: NP_000035.2, UniProt: P10275 |
Catalog # | MBS9404959 |
Price | $200, $255 |
Order / More Info | Androgen Receptor (Phospho-Tyr363) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |