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Antigenic Specificity | ASK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ASK1 activates two different subgroups of MAPKK, monkeyK4 and monkeyK6, which in turn activate c Jun N terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF alpha induced apoptosis. |
Immunogen | Immunogen: ASK1 antibody was raised in Rabbit using synthetic peptide corresponding to residue surrounding amino acid 1359 of human ASK1 as the immunogen. |
Other Names | [Rabbit ASK1/MAPKKK5; ASK1; ASK1; ASK1/MAPKKK5; MAPKKK5; Apoptosis Signal regulating Kinase 1; ASK1; ASK 1; ASK-1; ASK 1; ASK-1] |
Gene, Accession # | [ASK1], NCBI: CEP23956.1 |
Catalog # | MBS5309060 |
Price | $705 |
Order / More Info | ASK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |