PERK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPERK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1.4 mg/mL
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
ImmunogenImmunogen: KLH conjugated synthetic peptide corresponding to Human PERK
Other Names[DKFZp781H1925; E2AK3; EC 2.7.11.1; Eif2ak3; Eukaryotic translation initiation factor 2 alpha kinase 3; Eukaryotic translation initiation factor 2-alpha kinase 3; Heme regulated EIF2 alpha kinase; HRI; HsPEK; Pancreatic eIF2 alpha kinase; Pancreatic eIF2-alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; PRKR-like endoplasmic reticulum kinase; WRS]
Gene, Accession #[PERK], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5
Catalog #MBS2556379
Price$150, $225, $360
Order / More InfoPERK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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