Edit |   |
---|---|
Antigenic Specificity | HFE (Center), 122-148 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HFE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human HFE. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene. |
Immunogen | n/a |
Other Names | [Hereditary hemochromatosis protein; HLA-H; HFE; HLAH] |
Gene, Accession # | [HFE], Gene ID: 3077, NCBI: NP_000401.1, UniProt: Q30201 |
Catalog # | MBS9212894 |
Price | $165, $370 |
Order / More Info | HFE (Center), 122-148 Antibody from MYBIOSOURCE INC. |
Product Specific References | Valenti,L., Clin J Am Soc Nephrol 4 (8), 1331-1337 (2009) Won,J.E., Intervirology 52 (5), 239-246 (2009) |