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Antigenic Specificity | DICER |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody recognizes isoforms 1 and 2 of DICER. Dicer is an endoribonuclease which has two RNase III domains and one PAZ domain and belongs to the highly conserved family of dsRNA-specific endoribonucleases RNase III family. Dicer plays important roles in RNA processing, post-transcriptional gene expression control and defense against viral infection. Synthesis of proteins can be blocked by RNA in a process known as RNA interference and for this process to happen; three important events have to occur. First, DICER processes dsRNA into smaller fragments known as short interfering RNAs (siRNAs) and microRNAs (miRNAs). Second, a dsRNA binding protein recruits a DICER-siRNA complex to Argonaute2 (Ago2), which is an endonuclease capable of de |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [DICER] |
Catalog # | MBS588239 |
Price | $385 |
Order / More Info | DICER Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Daniels SM-HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs. |