p18INK4C Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | p18INK4C |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes p18INK4C protein. It crossreacts to human, mouse and rat. Others are not tested. Background:. Cyclin-dependent kinases (CDKs) are activated in part by forming complexes with cyclins. For example, CDK4 and CDK6 associate with the D-type cyclins ,md phosphorylate the retinoblastoma protein. This phosphorylation is a necessary event for cells to enter S-phase. The inhibitors of CDK4 (INK4) family include p151NK4B, p16 INK4A, p181NK4C and p19INK4D. p18 has been shown to function as a aploinsufficient tumor suppressor in vivo. All INK4 proteins are composed of 32 amino acid ankyrin motifs and selectively inhibit CDK4/6 activity. Mutational analyses of p18 implicate the third and the aminoterminal portion of the fourth an |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-terminus of Mouse p18INK4G. This sequence is identical to human, rat and mouse. |
| Other Names | n/a |
| Gene, Accession # | [p18INK4C], Gene ID: 1031 |
| Catalog # | MBS460113 |
| Price | $285 |
| Order / More Info | p18INK4C Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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