SEMA4D - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySEMA4D - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionCell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEMA4D
Other Names[semaphorin-4D isoform 2; Semaphorin-4D; semaphorin-4D; semaphorin 4D; A8; BB18; GR3]
Gene, Accession #[SEMA4D], Gene ID: 10507, NCBI: NP_001135759.1, UniProt: Q92854
Catalog #MBS3221595
Price$335
Order / More InfoSEMA4D - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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