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Antigenic Specificity | Mouse CD105 |
Clone | [MJ7/18] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD105 antibody, clone MJ7/18 recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumours. |
Immunogen | Immunogen: Inflamed mouse skin Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [endoglin isoform 1; Endoglin; endoglin; cell surface MJ7/18 antigen; transmembrane glycoprotein; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105], [Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg] |
Gene, Accession # | [CD105], Gene ID: 13805, NCBI: NP_031958.2, UniProt: Q63961 |
Catalog # | MBS219789 |
Price | $430 |
Order / More Info | Mouse CD105 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |