Mouse CD105 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD105
Clone[MJ7/18]
Host SpeciesRat
Reactive Speciesn/a
IsotypeIgG2a
Formatunconjugated
Size0.25 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsImmunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB)
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DescriptionRat anti Mouse CD105 antibody, clone MJ7/18 recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumours.
ImmunogenImmunogen: Inflamed mouse skin Buffer Solution: Phosphate buffered saline Target Species: Mouse
Other Names[endoglin isoform 1; Endoglin; endoglin; cell surface MJ7/18 antigen; transmembrane glycoprotein; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105], [Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg]
Gene, Accession #[CD105], Gene ID: 13805, NCBI: NP_031958.2, UniProt: Q63961
Catalog #MBS219789
Price$430
Order / More InfoMouse CD105 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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