UBAP1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | UBAP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: UBAP1 antibody detects endogenous levels of UBAP1. Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.Subunit Structure: Component of an ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, VPS37A and UBAP1 in a 1:1:1:1 stoichiometry. Can be a component of ESCRT-I complexes containing VPS37B, VPS37C and VPS37D (in vitro) (PubMed:22405001), but may have a preference for the ESCRT-I complex containi |
| Immunogen | Immunogen: A synthesized peptide derived from human UBAP1. Subcellular Location: Cytoplasm; Cytosol. Endosome. Note: Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex. Tissue Specificity: Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (83%), Bovine (92%), Horse (100%), Sheep (100%), Rabbit (92 |
| Other Names | [MGC8710; NAG20; Nasopharyngeal carcinoma associated gene 20 protein; UAP; UBAP 1; UBAP; Ubiquitin associated protein 1] |
| Gene, Accession # | [UBAP1], Gene ID: 51271, NCBI: NP_001164672.1, UniProt: Q9NZ09 |
| Catalog # | MBS9603292 |
| Price | $240, $280 |
| Order / More Info | UBAP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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