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Antigenic Specificity | ELL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ELL2 antibody detects endogenous levels of total ELL2. Function: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulat |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (83%) |
Other Names | [ELL related RNA polymerase II elongation factor; Ell2; ELL2_HUMAN; Elongation factor for RNA polymerase II 2; Elongation factor RNA for polymerase II 2; Elongation factor RNA polymerase II 2; RNA polymerase II elongation factor ELL2] |
Gene, Accession # | [ELL2], Gene ID: 22936, NCBI: NP_036213.2, UniProt: O00472 |
Catalog # | MBS9603770 |
Price | $240, $280 |
Order / More Info | ELL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |