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Antigenic Specificity | LRPPRC (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC. May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Leucine-rich PPR motif-containing protein; mitochondrial; 130 kDa leucine-rich protein; LRP 130; GP130; LRPPRC; LRP130] |
Gene, Accession # | [LRPPRC], Gene ID: 10128, NCBI: NP_573566.2, UniProt: P42704 |
Catalog # | MBS9215814 |
Price | $165, $370 |
Order / More Info | LRPPRC (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Xu F.,et al.Biochem. J. 382:331-336(2004).Ota T.,et al.Nat. Genet. 36:40-45(2004).Hillier L.W.,et al.Nature 434:724-731(2005).Hou J.,et al.In Vitro Cell. Dev. Biol. Anim. 30A:111-114(1994).Bienvenut W.V.,et al.Submitted (JUL-2007) to UniProtKB. |