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Antigenic Specificity | BRCA2 (pSer3291) [P-CS-4] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | 0.36mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phosphorylated BRCA2 (pSer3291). Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. |
Immunogen | Immunogen: Synthetic peptide linked to KLH |
Other Names | [BRCA2 (pSer3291) [P-CS-4]; BRCA 2; BRCA1/BRCA2 containing complex subunit 2; Brca2; BRCA2_HUMAN; BRCC 2; BRCC2; Breast and ovarian cancer susceptibility gene early onset; Breast cancer 2 early onset; Breast Cancer 2 tumor suppressor; Breast cancer susceptibility protein BRCA2; Breast cancer type 2 susceptibility protein; BROVCA2; FACD; FAD 1; FAD; FAD1; FANCB; FANCD 1; FANCD; FANCD1; Fanconi anemia complementation group D1 antibod; Fanconi anemia group D1 protein; GLM3; OTTHUMP00000018803; OTTHUMP00000042401], [BRCA2; BRCA2; FAD; FACD; FAD1; GLM3; BRCC2; FANCD; PNCA2; FANCD1; XRCC11; BROVCA2; FACD; FANCD1] |
Gene, Accession # | [BRCA2], Gene ID: 675, NCBI: AAB07223.1 |
Catalog # | MBS375415 |
Price | $450 |
Order / More Info | BRCA2 (pSer3291) [P-CS-4] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |