BRCA2 (pSer3291) [P-CS-4] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBRCA2 (pSer3291) [P-CS-4]
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentration0.36mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phosphorylated BRCA2 (pSer3291). Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures.
ImmunogenImmunogen: Synthetic peptide linked to KLH
Other Names[BRCA2 (pSer3291) [P-CS-4]; BRCA 2; BRCA1/BRCA2 containing complex subunit 2; Brca2; BRCA2_HUMAN; BRCC 2; BRCC2; Breast and ovarian cancer susceptibility gene early onset; Breast cancer 2 early onset; Breast Cancer 2 tumor suppressor; Breast cancer susceptibility protein BRCA2; Breast cancer type 2 susceptibility protein; BROVCA2; FACD; FAD 1; FAD; FAD1; FANCB; FANCD 1; FANCD; FANCD1; Fanconi anemia complementation group D1 antibod; Fanconi anemia group D1 protein; GLM3; OTTHUMP00000018803; OTTHUMP00000042401], [BRCA2; BRCA2; FAD; FACD; FAD1; GLM3; BRCC2; FANCD; PNCA2; FANCD1; XRCC11; BROVCA2; FACD; FANCD1]
Gene, Accession #[BRCA2], Gene ID: 675, NCBI: AAB07223.1
Catalog #MBS375415
Price$450
Order / More InfoBRCA2 (pSer3291) [P-CS-4] Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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