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Antigenic Specificity | DNAJA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 178-397 of human DNAJA1 (NP 001530.1). |
Other Names | [DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSJ-2; HSPF4; NEDD7; hDJ-2] |
Gene, Accession # | [DNAJA1], Gene ID: 3301, NCBI: P31689.2, UniProt: P31689 |
Catalog # | MBS8548072 |
Price | $280 |
Order / More Info | DNAJA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |