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Antigenic Specificity | RHOB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RHOB (NP 004031.1). |
Other Names | [ARH6; ARHB; RHOH6; MST081; MSTP081] |
Gene, Accession # | [RHOB], Gene ID: 388, NCBI: NP_004031.1, UniProt: P62745 |
Catalog # | MBS8545075 |
Price | $280 |
Order / More Info | RHOB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |