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Antigenic Specificity | Survivin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.50-1.50 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Baculoviral IAP repeat-containing protein 5 isoform 2 AntibodyMultitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effec |
Immunogen | Immunogen: Synthetic peptide corresponding to unique amino acid sequences on human Survivin protein. Expression: Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines. |
Other Names | [API4; Apoptosis Inhibitor 4; Apoptosis inhibitor survivin; Baculoviral IAP repeat-containing protein 5; BIRC 5; EPR 1; IAP4; Survivin variant 3 alpha; SVV; TIAP] |
Gene, Accession # | Gene ID: 332, NCBI: NP_001012270.1, UniProt: O15392 |
Catalog # | MBS5400007 |
Price | $390 |
Order / More Info | Survivin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |