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Antigenic Specificity | Human Proliferating Cell Nuclear Antigen |
Clone | [Pk1A3AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG3 |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation. |
Immunogen | Immunogen: Anti-human PCNA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PCNA amino acids 1-261 purified from E Coli. |
Other Names | [PCNA; Proliferating Cell Nuclear Antigen, Mouse Human; Proliferating cell nuclear antigen; PCNA; Cyclin; MGC8367], [PCNA] |
Gene, Accession # | [PCNA], NCBI: Q6FHF5 |
Catalog # | MBS140300 |
Price | $140, $205, $505 |
Order / More Info | Human Proliferating Cell Nuclear Antigen Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |