Human Proliferating Cell Nuclear Antigen Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Proliferating Cell Nuclear Antigen
Clone[Pk1A3AT]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG3
FormatProtein G purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionIntroduction: PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
ImmunogenImmunogen: Anti-human PCNA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PCNA amino acids 1-261 purified from E Coli.
Other Names[PCNA; Proliferating Cell Nuclear Antigen, Mouse Human; Proliferating cell nuclear antigen; PCNA; Cyclin; MGC8367], [PCNA]
Gene, Accession #[PCNA], NCBI: Q6FHF5
Catalog #MBS140300
Price$140, $205, $505
Order / More InfoHuman Proliferating Cell Nuclear Antigen Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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