Edit |   |
---|---|
Antigenic Specificity | PHAP I |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This polyclonal antibody has no cross-reaction to PHAP I2a and PHAP III. PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 |
Immunogen | Immunogen: PHAP I antibody was raised with a synthetic peptide corresponding to amino acids at carboxy terminus of human PHAP I. Buffer: PHAP I Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PHAP I; LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1; LANP; Acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic nuclear phosphoprotein pp32; acidic (leucine-rich) nuclear phosphoprotein 32 family, member A], [ANP32A; ANP32A; LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1; C15orf1; LANP; MAPM; PHAP1; pp32; LANP; PHAPI] |
Gene, Accession # | [ANP32A], Gene ID: 8125, NCBI: P39687.1, UniProt: P39687 |
Catalog # | MBS150933 |
Price | $375 |
Order / More Info | PHAP I Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |