CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) |
| Clone | [CR2/1952] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) / CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. |
| Immunogen | Immunogen: Recombinant human CR2 (CD21) protein fragment (around aa 44-196). Cellular Localization: Cell Surface |
| Other Names | [CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9], [CR2] |
| Gene, Accession # | [CD21], Gene ID: 1380, NCBI: NP_001006659.1, UniProt: P20023 |
| Catalog # | MBS439887 |
| Price | $190, $340, $340 |
| Order / More Info | CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Otsuka, M., et al. 2004. Role of CD21 antigen in diffuse large B-cell lymphoma and its clinical significance. Br. J. Haematol. 127: 416-424. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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