Human ALK6 (BMP R1B) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ALK6 (BMP R1B) |
| Clone | [3E12] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was selected for its ability to detect human ALK6. No cross reactivity was found to ALK3 (BMPR-IA). Cellular responses to bone morphogenetic proteins (BMPs) have been shown to be mediated by the formation of heterooligomeric complexes of the type I and type II serine/threonine kinase receptors. BMP receptor IB (BMPRIB), also known as activin receptor-like kinase (ALK)6, is one of seven known type I serine/threonine kinases that are required for the signal transduction of TGFbeta family cytokines. In contrast to the TGFbeta receptor system in which the type I receptor does not bind TGFbeta in the absence of the type II receptor, type I receptors involved in BMP signaling (including BMPRIA, BMPRIB/ ALK6, and ActRI/ ALK2) can ind |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human ALK6 extra cellular domain. IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. Antigen: Recombinant human ALK6 extracellular domain. |
| Other Names | [BMPR1B; ALK6; ALK-6, CDw293], [BMPR1B; BMPR1B; ALK6; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B] |
| Gene, Accession # | [ALK6 (BMP R1B)], Gene ID: 658, NCBI: NP_001194, UniProt: O00238 |
| Catalog # | MBS690053 |
| Price | $490 |
| Order / More Info | Human ALK6 (BMP R1B) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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