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Antigenic Specificity | Integrin alphaV |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Integrin alphaV antibody detects endogenous levels of total Integrin alphaV. Function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to FGF2 and this binding is |
Immunogen | Immunogen: A synthesized peptide derived from human Integrin alphaV Subcellular Location: Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (85%), Horse (92%), Sheep (85%), Rabbit (92%), Dog (100%) |
Other Names | [antigen identified by L230; CD 51; CD51; DKFZp686A08142; integrin alpha V beta 3; integrin alpha-V; Integrin alpha-V light chain; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITAV_HUMAN; ITGAV; MSK 8; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR] |
Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: NP_001138471.1, UniProt: P06756 |
Catalog # | MBS9601325 |
Price | $240, $280 |
Order / More Info | Integrin alphaV Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |