Phospho-CDK2 (Thr160) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CDK2 (Thr160) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-CDK2 (Thr160) antibody detects endogenous levels of CDK2 only when phosphorylated at Threonine 160. Description: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle.Function: Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional |
| Immunogen | Immunogen: A synthesized peptide derived from human CDK2 around the phosphorylation site of Threonine 160 Subcellular Location: Endosome; Nucleus; Cytoskeleton Tissue Specificity: Induced transiently by TGFB1 at an early phase of TGFB1-mediated apoptosis. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (91%) |
| Other Names | [Cdc2 related protein kinase; cdc2-related protein kinase; CDC28; CDC2A; Cdk 2; CDK1; CDK2; CDK2_HUMAN; CDKN2; Cell devision kinase 2; Cell division protein kinase 2; Cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2)] |
| Gene, Accession # | [CDK2], Gene ID: 1017, NCBI: NP_001277159.1, UniProt: P24941 |
| Catalog # | MBS9601008 |
| Price | $240, $280 |
| Order / More Info | Phospho-CDK2 (Thr160) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liang X, Sun R, Zhao X, Zhang Y, Gu Q, Dong X, Zhang D, Sun J, Sun B; Journal: J Cell Mol Med. Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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