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Antigenic Specificity | TMEM173 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TMEM173 Polyclonal Antibody detects endogenous levels of TMEM173 protein. TMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human TMEM173 |
Other Names | [Rabbit TMEM173; TMEM173; ERIS; MITA; STING; Transmembrane protein 173; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Stimulator of interferon genes protein; hSTING] |
Gene, Accession # | [TMEM173], Gene ID: 340061, NCBI: NP_938023.1, UniProt: Q86WV6 |
Catalog # | MBS9703870 |
Price | $130, $220, $325 |
Order / More Info | TMEM173 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |