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Antigenic Specificity | CD25/ IL2RA (Activated Lymphocyte Marker) |
Clone | [IL2RA/2395] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 55kDa, identified as CD25.It is expressed on activated T- and B-cells and activated monocytes/macrophages.With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ic chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block I |
Immunogen | Immunogen: Recombinantfragment of human IL2RA protein (around aa 42-183) Cellular Localization: Cell Surface and Cytoplasmic |
Other Names | [IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR] |
Gene, Accession # | [CD25], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589 |
Catalog # | MBS4380450 |
Price | $190, $340, $340 |
Order / More Info | CD25/ IL2RA (Activated Lymphocyte Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | T.A. Waldmann, et al, (1989) Annu Rev Biochem 58: 875-911. |