CD25/ IL2RA (Activated Lymphocyte Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD25/ IL2RA (Activated Lymphocyte Marker)
Clone[IL2RA/2395]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG2b
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 55kDa, identified as CD25.It is expressed on activated T- and B-cells and activated monocytes/macrophages.With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ic chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block I
ImmunogenImmunogen: Recombinantfragment of human IL2RA protein (around aa 42-183) Cellular Localization: Cell Surface and Cytoplasmic
Other Names[IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR]
Gene, Accession #[CD25], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589
Catalog #MBS4380450
Price$190, $340, $340
Order / More InfoCD25/ IL2RA (Activated Lymphocyte Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesT.A. Waldmann, et al, (1989) Annu Rev Biochem 58: 875-911.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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