CD257 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD257 |
| Clone | [7H149] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | ELISA (EL/EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Binds to CD257 in EIA and blocks binding of recombinant in Flow cytometry, and blocks binding of recombinant CD257-muCD8 to receptors on Raji cell surface in Flow cytometry. Human CD257 (B cell activating factor, BAFF,TALL-1, Blys, THANK) and CD256 (APRIL, a proliferation inducing ligand) are both type II molecules belonging to the TNF superfamily (TNFSFL #13b and 13 respectively). They are expressed by non-B cells, and are down regulated by mitogenic stimulation(2). BAFF and APRIL bind to at least two receptors: CD267 (TACI, transmembrane activator and CAML-interactor) and CD269 (BCMA, B cell maturation antigen), both of which are restricted to B cells(3,4). Ligation of these receptors with recombinant BAFF dramatically increa |
| Immunogen | Immunogen: Recombinant soluble human CD257. Functional Application: Antibody blocks binding of Recombinant CD257(BAFF) to Raji cell surface. |
| Other Names | n/a |
| Gene, Accession # | NCBI: AEC04786.1 |
| Catalog # | MBS602561 |
| Price | $515 |
| Order / More Info | CD257 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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