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Antigenic Specificity | PPP2R2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PPP2R2B protein. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022]. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human PPP2R2B. |
Other Names | [Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; PP2A subunit B isoform B55-beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A subunit B isoform beta] |
Gene, Accession # | [PPP2R2B], Gene ID: 5521, NCBI: NP_001258828.1, UniProt: Q00005 |
Catalog # | MBS9414527 |
Price | $200, $255 |
Order / More Info | PPP2R2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |