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Antigenic Specificity | CDK14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.2mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CDK14 protein. Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. |
Immunogen | Immunogen: Synthetic peptide of human CDK14 Immunogen Type: Peptide |
Other Names | [PFTK1; PFTAIRE1] |
Gene, Accession # | [CDK14], Gene ID: 5218, NCBI: NP_001274064.1, UniProt: O94921 |
Catalog # | MBS9417213 |
Price | $255 |
Order / More Info | CDK14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |