Phospho-Ser311, Thr315 MEK5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Ser311, Thr315 MEK5
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Specific for the ~49k MEK5 protein phosphorylated at Ser311, Thr315. Immunolabeling of the MEK5 band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding dephospho-peptide. Affinity purified rabbit polyclonal antibody
ImmunogenAntigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser311/Thr315 conjugated to KLH. Immunogen Species: Rat
Other Names[dual specificity mitogen-activated protein kinase kinase 5 isoform a; Dual specificity mitogen-activated protein kinase kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MEK 5; MAPKK 5; MAPK/ERK kinase 5; MAP kinase kinase 5; mitogen activated protein kinase kinase 5; MAPK/ERK kinase 5], [Map2k5; Map2k5; Mek5; Mek5; Mkk5; Prkmk5; MAP kinase kinase 5; MAPKK 5; MEK 5]
Gene, Accession #[MAP2K5], Gene ID: 29568, NCBI: NP_001029159.1, UniProt: Q62862
Catalog #MBS502075
Price$360
Order / More InfoPhospho-Ser311, Thr315 MEK5 Antibody from MYBIOSOURCE INC.
Product Specific References• Zhou G, Bao ZQ, Dixon JE, (1995) Components of a new human protein kinase signal transduction pathway. J. Biol. Chem. 270(21):12665-9.• Chao TH, Hayashi M, Tapping RI, Kato Y, Lee JD (1999) MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway. J. Biol. Chem. 274(51):36035-8.• Mehta PB, Jenkins BL, McCarthy L, Thilak L, Robson CN, Neal DE, Leung HY (2003) MEK5 overexpression is associated with metastatic prostrate cancer, and stimulates proliferation, MMP-9 expression and invasion. Oncogene 22(9):1381-9.• Cameron SJ, Abe J, Malik S, Che W, Yang J (2004) Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation. J. Biol. Chem. 279(2):1506-12.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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