Human CD28 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD28 |
| Clone | [ANC28.1/5D10] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | phycoerythrin (RPE) conjugate |
| Size | 120 tests |
| Concentration | Volume: 0.2 ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Agonist |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD28 is an important costimulatory molecule found on all CD4 T cells and on about half of the CD8 T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA and activation of CD8 cytotoxic T lymphocytes. the ligands for CD28 identified as CD80(B7-1) and CD86(B7-2), are immunglobulin superfamily monomeric transmembrane glycoproteins of 60 kd and 80 kd respectively. Anti-CD28 antibodies have recently been shown to have a strong adjuvant effect when conjugated to the immunogen (4). Antibody ANC28.1 recognizes CD28 expressed on human T cells and also on BHK cells transfected with human CD28. Monomeric and cross linked ANC28.1 will stimul |
| Immunogen | Immunogen: Recombinant Human CD28 and HPB-MLT human tumor cells |
| Other Names | [human CD28/R-PE], [Cd28; Cd28] |
| Gene, Accession # | [CD28], Gene ID: 12487, NCBI: AAA37396.1 |
| Catalog # | MBS666199 |
| Price | $470 |
| Order / More Info | Human CD28 Antibody from MYBIOSOURCE INC. |
| Product Specific References | (1) M.K. Jenkins & J.G. Johnson, (1993) Curr Opin Immunol 5: 361-367. (2) 61st Forum in Immunology, (1995) Res Immunol 146: 127-205. (3) I. Kariv, A. Truneh & R.W. Sweet, (1996) J Immunol 157: 29-38. (4) J. Carling, et al, (2003) J Immunol 33: 135-142. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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