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Antigenic Specificity | GZMB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human GZMB (NP 004122.2). |
Other Names | [C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1] |
Gene, Accession # | [GZMB], Gene ID: 3002, NCBI: NP_004122.2, UniProt: P10144 |
Catalog # | MBS8544988 |
Price | $280 |
Order / More Info | GZMB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |