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Antigenic Specificity | IL-23 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-α from activated T cells, and can stimulate macrophages to produce TNF-α and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer. |
Immunogen | Immunogen: IL-23 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-23. Buffer: IL-23 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-23; P19; SGRF; IL-23; IL-23A; IL23P19; UNQ2498/PRO5798; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; IL-23 subunit alpha; interleukin 23, alpha subunit p19], [IL23A; IL23A; P19; SGRF; IL-23; IL-23A; IL23P19; SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19] |
Gene, Accession # | [IL23A], Gene ID: 51561, NCBI: AAH66268, UniProt: Q9NPF7 |
Catalog # | MBS151355 |
Price | $375 |
Order / More Info | IL-23 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |