Edit |   |
---|---|
Antigenic Specificity | Human Transcriptional repressor CTCF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprint |
Immunogen | Immunogen: Recombinant human Transcriptional repressor CTCF protein(1-260aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5916 / sc-15913 / sc-15914 / sc-28198 |
Other Names | [11-zinc finger protein; CCCTC-binding factor; CTCFL paralog; CTCF], [CTCF; CTCF; MRD21] |
Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711 |
Catalog # | MBS1495762 |
Price | $120, $160 |
Order / More Info | Human Transcriptional repressor CTCF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |