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Antigenic Specificity | CNOT10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CNOT10 protein. CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway |
Immunogen | Immunogen: Fusion protein of human CNOT10 Immunogen Type: Protein |
Other Names | [Homo sapiens CCR4-NOT transcription complex, subunit 10, mRNA; CCR4-NOT transcription complex subunit 10; CCR4-NOT transcription complex subunit 10; CCR4-NOT transcription complex subunit 10] |
Gene, Accession # | [CNOT10], Gene ID: 25904, NCBI: BC002931, UniProt: Q9H9A5 |
Catalog # | MBS9429911 |
Price | $255 |
Order / More Info | CNOT10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |