Human Amyloid beta A4 precursor protein-binding family B member 1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Amyloid beta A4 precursor protein-binding family B member 1 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Amyloid beta A4 precursor protein-binding family B member 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Required for histone H4 acetylation at double-strand breaks (DSBs). Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, probably explains its trancription activation |
| Immunogen | Immunogen: Recombinant human Amyloid beta A4 precursor protein-binding family B member 1 protein (361-710aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19750 / sc-19751 / sc-33155 |
| Other Names | [Protein Fe65; APBB1; FE65; RIR], [APBB1; APBB1; RIR; FE65; MGC:9072; FE65; RIR] |
| Gene, Accession # | [APBB1], Gene ID: 322, NCBI: NP_001155.1, UniProt: O00213 |
| Catalog # | MBS1494446 |
| Price | $120, $160 |
| Order / More Info | Human Amyloid beta A4 precursor protein-binding family B member 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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