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Antigenic Specificity | TMEM100 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex. |
Immunogen | Immunogen: Recombinant human Transmembrane protein 100 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165724 / sc-165726 / sc-165727 |
Other Names | [Transmembrane protein 100; TMEM100], [TMEM100; TMEM100] |
Gene, Accession # | [TMEM100], Gene ID: 55273, NCBI: NP_001093110.1, UniProt: Q9NV29 |
Catalog # | MBS1492945 |
Price | $160, $235 |
Order / More Info | TMEM100 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |