CLDN8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CLDN8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CLDN8 antibody detects endogenous levels of total CLDN8. Function: Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.Subunit Structure: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with CLDN4. Interacts with KLHL3.Post-translational Modifications: Ubiquitinated by the BCR(KLHL3) E3 ubiquitin ligase complex in the kidney, leading to its degradation.Similarity: Belongs to the claudin family. |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Junction > Tight Junction. Cell Membrane. Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells. Tissue Specificity: Expressed in the epididymis, mainly in the caput segment. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit Similarity: Bovine (82%), Horse |
| Other Names | [Claudin 8; Claudin-8; CLD8_HUMAN; Cldn8; Epididymis secretory protein Li 79; HEL S 79; OTTHUMP00000101915] |
| Gene, Accession # | [CLDN8], Gene ID: 9073, NCBI: NP_955360.1, UniProt: P56748 |
| Catalog # | MBS9605403 |
| Price | $240, $280 |
| Order / More Info | CLDN8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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